5 results
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... #Vasopressors #Inotropes ... #comparison #table ... #pharmacology # ... criticalcare
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
beta adrenergic receptors ... force (negative inotropy ... ) ACCP Cardiology ... Vaughan #Williams #Pharmacology ... pathophysiology #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... beta adrenergic receptors ... force (negative inotropy ... ) ACCP Cardiology ... Antiarrhythmics #Pharmacology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
• Heart - ↑ Inotropy ... Norepinephrine release ... Adrenoceptor #adrenergic #receptors ... #actions #pharmacology ... pathophysiology #comparison
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... mineralocorticoid receptor ... infarction, moderate to severe ... Cardiotoxicity #cardiology ... #oncology #pharmacology