31 results
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Demystified Shock ... Vasopressors #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Extreme Dehydration, Severe ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... inopressors #diagnosis #management ... #comparison #table
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Pathophysiology Comparison ... vasodilatation and release ... valvular disease. severe ... myocarditis, or severe ... #Comparison #criticalcare
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... Vasopressors #Inotropes #management ... #criticalcare # ... summary #comparison ... #table #pharmacology
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors #Inotropes #criticalcare ... #pharmacology # ... comparison #shock ... #management
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... , Shock where ↑ ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare
NSAIDs and GI versus CV risk

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#pharmacology #comparison #cardiology #gi #nsaids #pain #medications #management
#pharmacology #comparison ... #cardiology #gi ... #medications #management
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... #Diuretics #Pharmacology ... #Comparison #Table ... Thiazide #CHF #Cardiology ... #Management
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... poor PO intake, severe ... uw_IMresidency #Shock ... Diagnosis #table #comparison ... #criticalcare
American College of Critical Care Medicine algorithm for time-sensitive, goal-directed stepwise management of hemodynamic support in
goal-directed stepwise management ... to next step if shock ... not reversed proceed ... #CriticalCare # ... Pediatrics #Sepsis #Management