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diagnosis hematology causes algorithm anemia comparison diffuse hairloss hemolytic hodgkins leukemia management rheumatology workup agglutinin allergy apml ascites cd4 cell
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Richter’s Syndrome ... Intussusception, SIB ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... and secondary lymphoid ... lymphoma #Leukemia ... #Hematology #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diffuse and Focal) Differential ... • Loose anagen syndrome ... totalis (all scalp ... universalis (all ... #dermatology #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... , lymphoma, idiopathic ... Extravascular #Causes #differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... (HCV) • CLL & ... Marginal zone lymphoma ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... accounts for 10% of all ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
) - Differential ... • Loose anagen syndrome ... totalis (all scalp ... universalis (all ... #dermatology #Differential
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
Facial Swelling - Differential ... Preeclampsia Dermatologic ... • Cutaneous lymphomas ... - CLL Others ... Swelling #Edema #Differential
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... Primary: - CML ... - Lymphomas ... Hypereosinophilic Syndrome ... Diagnosis #Causes #hematology
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