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diagnosis management hemophagocytic lymphohistiocytosis oncology arteritis classification gca giantcell hemeonc hodgkins lymphoma mds myelodysplasia myelodysplastic plasmacytoma signs solitary summary symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Purtilo (XLP) Acquired ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Low or absent NK cell ... • Bicytopenia Treatment ... Supportive measures and treating ... diagnosis #management #treatment ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... adsorption onto cancer cells ... EricsMedicalLectures/ #Acquired ... Diagnosis #Management #treatment ... #hematology #differential
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and treatment ... search for and treatment ... • Secondary (Acquired ... Treatment Approach ... Diagnosis #Management #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Reed-Sternberg cells ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... : Goals: Treating ... Syndromes #diagnosis #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... very remarkable w/differential ... Treatment of GCA ... them, but urgent rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
marrow, e.g., ribs ... the periphery, creating ... • Vertebrae • Ribs ... Bone marrow Treatment ... Diagnosis #Workup #Hematology
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