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management pulmonary antigbm basement disease giomeruiar goodpastures hemophagocytic hlh lymphohistiocytosis membrane myelitis nephrology neurology prs renal rheumatology summary syndromes transverse
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... #management #treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... Renal #Syndromes #differential ... #treatment
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
hemorrhage Diagnosis ... : • Anti-GBM antibodies ... kidney biopsy Treatment ... Daily sessions to clear ... Goodpastures #AntiGBM #diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
levels • NMO-IgG (anti-AQP4 ... Brucellosis - Dengue, EBV ... AntiCRMP IgG, Anti-Hu ... Transverse Myelitis Treatment ... management #neurology #differential
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