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differential management rheumatology vasculitis algorithm classification hiv neurology acute adultonset aids anti antigbm atopic atopy basement cns contusion ctchest dermatitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... to Kidney: Anti-GBM ... With associated pulmonary ... Disease (Goodpasture's ... #differential #diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... Coxsackie, CMV, EBV ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... #management #treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... for alternative causes ... HBV, HCV, HEV, EBV ... Alcohol-related liver disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... progressing GN • New pulmonary ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... Differential Diagnosis
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
dermatitis, a disease ... This disease imposes ... #diagnosis #causes ... References: Danby SG ... Petersen EBM, Skov
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... tract, and often causes ... pain and GN Anti-GBM ... #Differential #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... supraclavicular node • Anterior ... lymph node biopsy (diagnostic ... number of sites of disease ... Hodgkin Lymphoma Treatment
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Infectious causes ... Brucellosis - Dengue, EBV ... MCTD - Bechet disease ... Transverse Myelitis Treatment
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