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differential management rheumatology classification algorithm anti antigbm atopic atopy basement contusion ctchest dermatitis dermatology disease eczema giomeruiar glomerulonephritis goodpastures hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... to Kidney: Anti-GBM ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... #differential #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Treatment: • ... of emergency, ICU
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... progressing GN • New pulmonary ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... Differential Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... tract, and often causes ... pain and GN Anti-GBM ... #Differential #Diagnosis
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
recommendations, treatments ... #medications #treatment ... #diagnosis #causes ... References: Danby SG ... Petersen EBM, Skov
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Infectious causes ... Brucellosis - Dengue, EBV ... - Sjogren - Vasculitis ... Transverse Myelitis Treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... supraclavicular node • Anterior ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
A small vessel vasculitis ... hemorrhage Diagnosis ... : • Anti-GBM antibodies ... kidney biopsy Treatment ... #nephrology #pulmonary
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
(@MarkRamzyDO, EM ... Hamilton, MD (EM ... over the left anterior ... Several of the diagnoses ... over the left anterior
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