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management differential neurology hematology oncology syndrome barre cns guillain hiv hodgkins infectiousdiseases lymphoma rheumatology 1 acute adultonset aids algorithm anemia
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... of emergency, ICU
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
., HIV), EBV infection ... Autoimmune diseases • Clinical ... Etiology: - Infections ... Differential Diagnosis ... comparison #oncology #diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... : • Infectious ... Coxsackie, CMV, EBV ... #management #treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... HBV, HCV, HEV, EBV ... Liver #Injury #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Neutropenia - recurrent infections ... Idiopathic • Infections ... aplastic anemia Treatment ... oncology #hematology #diagnosis
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
loss (>5 lb; 2.5 kg ... Epstein-Barr virus (EBV ... Viral hepatitis Diagnosis ... antibody test) Treatment ... Syndrome #HIV #diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
myasthenia Diagnosis ... and EMG Findings ... Bedside: ice pack ... precipitated by: Drugs, infection ... Myasthenia #Gravis #diagnosis
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
response preceding infection ... - HIV, CMV, EBV ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... #management #treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... GrepMed Handbook Clinical ... Acute Diarrhea (>3 BM ... #1 nosocomial infection ... Bezlotoxumab 10 mg/kg
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
transplantation CLINICAL ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT ... specific therapy, the clinician ... intensive care unit (ICU
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