10 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Treatment: • ... of emergency, ICU ... #management #treatment
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... Subacute to Chronic Causes ... #differential #diagnosis
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
COVID19 in the ICU ... data on mortality rate ... Epidemiology • Attack rate ... 31 • First US case ... : Marino's The ICU
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... start and stop dates ... non-essential drug/HDS treatments ... for alternative causes ... HBV, HCV, HEV, EBV
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... CRITERIA FOR ICL ... EBV. CMV. ... #Lymphopenia #ICL ... #Differential #Causes
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... pregnancy, or other causes ... Diagnosis and Context ... #cullensign #em ... peritonitis #IM #FM #ICU
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
include Crackles/Rales ... & Dry) is the treatment ... the determined cause ... & Dry” is the treatment ... #criticalcare #icu
Management of Marine Envenomations
 • North American Cnidaria - Hot water, Supportive care
 • Irukandji jellyfish
6% acetic acid, ice ... 6% acetic acid, ice ... Antivenom for severe cases ... antibiotics EB ... Envenomations #Management #treatment
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... - Lymphocyte rich ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... Standard treatment ... survival by 25% ↑ ICP ... to normalize ICP ... approximately 15% ↑ in rate