7 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... and Evidence Summary ... - NEJM 1999 - ICU ... NEJM 2013 - UGIB TRISS ... /vmoitra) #EBM
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
- A Randomized Clinical ... Trial JAMA. ... admitted to the ICU ... #TTM48 #TTH48 #CriticalCare ... #EBM
POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients
POLAR Randomized Clinical ... Trial - Effect ... Hypothermia #TBI #CriticalCare ... #ICU #VisualAbstract ... #EBM
REVISE - Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical
Pilot Randomized Clinical ... Trial and Meta-Analysis ... #Prophylaxis #CriticalCare ... #ICU #Withholding ... VisualAbstract #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... and biological evidences ... Assessment • Clinical ... Ferritin >1000 ng ... of emergency, ICU
Septal Hypertrophic Cardiomyopathy (HOCM)

52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) 
EM resident
Septal Hypertrophic Cardiomyopathy ... Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... #HOCM #HCM #clinical
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
nurses well, pay ICU ... Enroll patient in a clinical ... trial Don't ... Factors #Matter #EBM ... Improve #Outcomes #Evidence