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diagnosis neurology cns disease ebm hematology icu rheumatology sepsis treatment adultonset agglutinin aids anemia classification cold criteria effectiveness encephalitis evidence
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
- A Randomized Clinical ... admitted to the ICU ... #TTM48 #TTH48 #CriticalCare ... #ICU #VisualAbstract ... #EBM
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
host response to infection ... Clinical construct ... was defined as positive ... #QSOFA #SIRS #criticalcare ... #icu
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV ... Disease #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Clinical Presentation ... dehydrogenase • Positive ... - Mycoplasma, EBV ... younger pts) Differential
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... should be based on clinical ... effect/Edema • EBV ... and <25% culture positive ... #differential #
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... • Common clinical ... • Gram stain: Positive ... 90% • Culture: Positive
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Direct microbial infection ... Transverse Myelitis - Clinical ... Brucellosis - Dengue, EBV ... Myelitis #diagnosis #management ... #neurology #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... infection • Family ... Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... hematology #oncology #management
Sepsis - Interventions that do / do not improve outcomes Do: - Have high index of suspicion and
Talk to others - infectious ... nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM
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