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neurology treatment cns disease hematology infections rheumatology adultonset agglutinin aids anemia cardiology cardiomyopathy ck classification cold creatine elevated encephalitis gravis
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... immobility • Critical ... Illness Myopathy (ICU ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... biologics (CMV +++, EBV ... of emergency, ICU ... #management #treatment
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • ... Coxsackie, CMV, EBV ... #management #treatment
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
Bacterial Meningitis - Differential ... virus • CMV • EBV ... • Common clinical ... • Gram stain: Positive ... 90% • Culture: Positive
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... dehydrogenase • Positive ... - Mycoplasma, EBV ... younger pts) Differential ... Diagnosis Monoclonal
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... myasthenia Diagnosis ... Bedside: ice pack ... Myasthenia #Gravis #diagnosis ... #management #neurology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Clinical • Under-recognized ... Avoid ARBs • ICD ... teratogenic GDMT meds ... Cardiomyopathy #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... and usually CD15 positive ... hematology #oncology #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
in HIV / AIDS - Differential ... should be based on clinical ... effect/Edema • EBV ... and <25% culture positive ... CNS #Infections #differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... Brucellosis - Dengue, EBV ... #management #neurology ... #differential
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