6 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... #management #treatment
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... admission to the ICU ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... physical exam, CT ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... Coxsackie, CMV, EBV ... Visceral, DIC, TMA ... #management #treatment ... #rheumatology
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Epigastric abdominal pain (90%, characteristically
and Management ... , gallstones), CT ... pain-dose ketamine (ICU ... Tx: ABx (pip-tazo ... #Management #Treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
and Management ... Acute Diarrhea (>3 BM ... equivocal • CT ... Management (IDSA ... #management #treatment