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differential management barre causes guillain syndrome ck clinical cns creatine elevated encephalitis eyelid gbs generalized guillainbarre kinase meningitis ocular ophthalmology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... : - Bedside: ice ... aspiration and acute ... #Gravis #diagnosis ... #management #neurology
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
non-localized EOM ... weakness and bilateral ... Myasthenia gravis ... cogan sign and the ice ... ophthalmology #neurology
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 Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... - Differential Diagnosis ... : Influenza, EBV ... NMJ disorder (Myasthenia ... #causes #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Impairment: • Acute ... Postsynaptic: Myasthenia ... Gravis - Lack ... Coxsackie, HIV, CMV, EBV ... #neurology
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Elevated CK Levels Acute ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... Myocardial infarction, Acute ... #differential #diagnosis
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Syndrome - Summary Acute ... response preceding infection ... - HIV, CMV, EBV ... variants: (1) acute ... management #treatment #neurology
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Viruses (HSV, EBV ... Miller-Fisher GBS; Positive ... lymphoma OTHERS - Acute ... #Differential #Diagnosis ... #Causes #Neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Syndrome (GBS) Acute ... progressive flaccid weakness ... to a preceding infection ... intensive care unit (ICU ... #management #neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... Symptoms: • Acute ... • Gram stain: Positive ... #neurology #meningitis
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