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causes infections agglutinin aids algorithm anemia betadglucan biomarkers brain ck cold comparison cord creatine disease disorders elevated encephalitis fungal galactomannan
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
granulomatosis: • EBV-associated ... cryptococcus, and aspergillus ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
- Other positives ... cut-offs defined in clinical ... BAL GM does not differentiate ... - Frozen ice-pops ... Galactomannan #diagnosis
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Viruses (HSV, EBV ... Influenza A FUNGAL - Aspergillus ... Miller-Fisher GBS; Positive ... #Diagnosis #Causes ... #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... should be based on clinical ... effect/Edema • EBV ... and <25% culture positive ... #Infections #differential
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... immobility • Critical ... Illness Myopathy (ICU ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... • Common clinical ... Singh @rav7ks #CNS ... #diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Diagnosis Framework ... neurological lesion: Clinical ... Mycoplasma, Influenza, EBV ... Coccidioides, Aspergillus ... #neurology #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Viral Infection Clinical ... dehydrogenase • Positive ... - Mycoplasma, EBV ... younger pts) Differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Brucellosis - Dengue, EBV ... #management #neurology ... #differential
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