21 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Chorioretinitis • Diagnosis ... - Compatible syndrome ... granulomatosis: • EBV-associated ... #differential #diagnosis ... causes #radiology #neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... cells per μL • Diagnosis ... Antimicrobial treatment ... effect/Edema • EBV ... and <25% culture positive
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... #management #treatment
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
Guillain-Barre Syndrome ... suspect 2️⃣ How to Diagnose ... When to admit to ICU ... 5️⃣ Treatment ... #Management #Neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... pulmonary etc) • CNS ... Coxsackie, HIV, CMV, EBV ... #Differential #Diagnosis ... #neurology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Fanconi's syndrome ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM ... #Proteinuria #Nephrology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Skin lesions • Positive ... Arthritis, AS Treatment
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Viruses (HSV, EBV ... - Bickerstaff syndrome ... Miller-Fisher GBS; Positive ... #Differential #Diagnosis ... #Causes #Neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... myasthenia Diagnosis ... : - Bedside: ice ... Myasthenia #Gravis #diagnosis ... #management #neurology