16 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... myasthenia Diagnosis ... : - Bedside: ice ... #diagnosis #management ... #neurology
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia Gravis ... non-localized EOM ... Myasthenia gravis ... cogan sign and the ice ... ophthalmology #neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... #management #treatment
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
Guillain-Barre Syndrome ... suspect 2️⃣ How to Diagnose ... When to admit to ICU ... 5️⃣ Treatment ... #Management #Neurology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Fanconi's syndrome ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM ... #Proteinuria #Nephrology
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Viruses (HSV, EBV ... - Bickerstaff syndrome ... Miller-Fisher GBS; Positive ... #Differential #Diagnosis ... #Causes #Neurology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
infections (HPV, EBV ... (Goodpasture's syndrome ... #differential #diagnosis ... urine #management #treatment ... #nephrology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... Postsynaptic: Myasthenia Gravis ... Coxsackie, HIV, CMV, EBV ... #Differential #Diagnosis ... #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
from a seated position ... Atorvastatin Diagnosis ... - SAMS <20,000 IU ... : 1,000–20,000 IU ... toxicity #myopathy #diagnosis