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diagnosis rheumatology management causes comparison msk physicalexam algorithm apml aspergillus autoimmune betadglucan biomarkers bowel classification cppd differentiation effusions erythematosus extremity
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential ... Fever/Chills/Joint ... Seronegative Reactive Syndrome ... Acute rheumatic fever ... Effusions: - Hematologic
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Infancy (SUDI) - Differential ... Sudden Infant Death Syndrome ... 80% of SUDI • Risk ... Algorithm #Causes #Peds ... #Pediatrics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... initiation • Differential ... diagnosis #management #hematology ... #oncology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
inflammatory response Risk ... • Metabolic syndrome ... forefoot, ankles, knees ... 12-24 Hours • Fever ... #Comparison #rheumatology
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... Arthritis • Gout ... injury • DVT (Risks ... pain/swelling - Fever ... #Leg #pain #differential
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
inflammatory response Risk ... sex • Metabolic syndrome ... forefoot, ankles, knees ... 12-24 Hours • Fever ... drug failure • Risk
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary Use a positive diagnostic strategy with minimal testing.
Irritable Bowel Syndrome ... those at high risk ... missing things" → fewer ... Gastroenterology and Hepatology ... Irritable #Bowel #Syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... blood count with differential ... and reducing the risk ... #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... vein thrombosis Hematologic ... to: Arthritis, Fever ... Thrombosis highest risk
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) in hematologic ... useful in high risk ... BAL GM does not differentiate ... post-2010 almost never ... or GVHD (leaky gut
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