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diagnosis betadglucan fungal galactomannan infectiousdiseases management pulmonary rheumatology abscess addisons adrenal aids aspergillus biomarkers causes classification disease endocrinology erythematosus falsepositives
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : Temperature rises ... Brucellosis Faget's Sign ... For every 1°F rise ... Brucellosis • Liver or lung
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Disorders: • Infection ... tuberculosis, fungal infections ... Adrenals: • Lung ... hypotension develops • Risk ... • Low-grade fever
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... • CT: Halo sign ... Pneumonia: • Risk ... #Infections #HIV
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Food products Risk ... Presentation: Fever ... Pulmonary Disease: Clinical ... Disease: • Clinical ... #differential #
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • DM risk ... Lung Abscess - Clinical ... : • 80% have fever ... Abscess Differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
invasive fungal infection ... cut-offs defined in clinical ... useful in high risk ... BAL GM does not differentiate ... Galactomannan #diagnosis #comparison
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... weight loss, and fever ... permanent alopecia Differential ... fibromyalgia) • Infections ... Thrombosis highest risk
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
disease Malignancy Risk ... and increased risk ... dermatomyositis) Malignancy Risk ... and increased risk ... and increased risk
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
surfaces, Albumin, Infections ... >90% (In most clinical ... useful in high risk ... in BAL does not differentiate ... result in + as long
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... History of EBV infection ... Immunosuppression • Autoimmune ... Hodgkin Lymphoma - Clinical ... • Dyspnea • Fever
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