12 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Fever/Chills/Joint ... Infectious Knee ... Alphavirus - Fungi ... arthritis - SLE
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... noninflammatory Signs ... • Rheumatic fever ... • Lyme • Gout ... arthritis • SLE
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... 9) Unexplained fever ... , when infection ... including in children (pediatric ... erythematosus #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... Diagnose concomitant infection ... drug failure • Risk
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) ... surfaces - Infections ... useful in high risk ... BAL GM does not differentiate ... or GVHD (leaky gut
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
diagnose concomitant infection ... inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... #Comparison #rheumatology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Pseudomonas FUNGAL ... • CT: Halo sign ... Pneumonia: • Risk
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... fibromyalgia) • Infections ... to: Arthritis, Fever ... Thrombosis highest risk
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
surfaces, Albumin, Infections ... useful in high risk ... in BAL does not differentiate ... post-2010 almost never ... or GVHD (leaky gut
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... purpura: Strong sign ... purpura, joint & gut ... #Diagnosis #Rheumatology