14 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Findings Risk ... Apolipoprotein E4 allele Risk ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Attempt if high risk ... Diagnosis: >3 symptoms ... management #hematology #oncology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pathogenesis and clinical ... Patients at Risk ... Constipation - MSK ... #diagnosis #pathophysiology ... #symptoms #signs
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... myopathies such as ... muscle fibers Risk ... Pitavastatin Risk ... IU/I • SAMS clinical
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... Risk Factors: ... overload) Other Symptoms ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
that are poorly formed ... age 70 years Symptoms ... carries a variable risk ... and reducing the risk ... diagnosis #hematology #oncology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
carry treatment ... for Refeeding Syndrome ... risk causing Hypoglycemia ... algorithm #management #treatment ... #criticalcare #foamed
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... in improperly folded ... fasciculations Common Symptoms ... Dysphagia- increased risk ... diagnosis column Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Risk factors 3. ... edema visualized as ... epilepticus Treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Bone Groups at risk ... poor nutrition Clinical ... and tachypnea As ... nonimmune hemolysis MSK ... vasculitis Treatment