16 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... for VTE - Dr. ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... #coumadin #rivaroxaban ... #Xarelto #apixaban ... #Eliquis #dabigatran
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Management Cheat Sheet: Warfarin ... , Apixaban, Dabigatran ... , Rivaroxaban ... #Anticoagulant
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Clotting Time Warfarin ... Fondaparinux Rivaroxaban ... Apixaban, Edoxaban ... Argatroban Dabigatran ... #Testing #Diagnosis
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Xa Inhibitors: Rivaroxaban ... , Apixaban, Edoxaban ... K Antagonists: Warfarin ... Inhibitors: Argatroban, Dabigatran ... #anticoagulation
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban ... Edoxaban (Lixiana), Rivaroxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
: Apixaban (25% ... patients 5mg bid Dabigatran ... OralAnticoagulant #Anticoagulation ... #Pharmacology #Apixaban ... #Rivaroxaban #Dabigatran
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... Agents Warfarin ... Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... Hepatic, 50% Renal Rivaroxaban
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Pathophysiology Anticoagulation ... the mainstay of VTE ... (e.g. warfarin) ... LMWH #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban
Anticoagulant Sites of Absorption
Apixaban - Primarily proximal small intestine; some gastric absorption
Dabigatran - Lower stomach and
of Absorption Apixaban ... gastric absorption Dabigatran ... small intestine Rivaroxaban ... gastric absorption Warfarin ... Sites #Absorption #anticoagulation