15 results
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g AEIOU ) or anuria ... : Hypovolemia, Low ... Urinary obstruction, Nephrotoxic ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... and Differential Diagnosis ... • Interstitial nephritis ... #nephrology #causes
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Gradient (SAAG) ... Veno-occlusive disease - Acute ... Mixed ascites" Low ... without cirrhosis - Nephrotic ... #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
If the value is low ... result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... : • Low serum IgG ... DDX - Other causes ... hypogammaglobulinemia: • Nephrotic ... hypogammaglobulinemia #immunology #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... • Elevation of serum
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... infections are common causes ... glomerular #testing #workup ... #diagnosis #glomerulonephritis ... #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... Classification: • Acute ... , and elevated serum ... , lymphopenia, low ... PLT • Anemia of
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... infections are common causes ... glomerular #disease #workup ... #diagnosis #initial ... #testing #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis