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management rheumatology lupus testing disease erythematosus glomerular systemic acute aki alkaline alp arthritis classification common comparison cvid druginduced gammopathy glomerulonephritis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... ulcers, Lupus nephritis ... • Immunologic Workup ... Positive in 60-80% of cases ... 60-80% - Low
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
e.g AEIOU ) or anuria ... : Hypovolemia, Low ... Urinary obstruction, Nephrotoxic ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... in >90% - Low ... Discontinuation of causal ... ulcers, Lupus nephritis ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... Differential Diagnosis ... , and elevated serum ... , lymphopenia, low ... PLT • Anemia of
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
If the value is low ... result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... : • Low serum IgG ... DDX - Other causes ... hypogammaglobulinemia: • Nephrotic ... hypogammaglobulinemia #immunology #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... • Elevation of serum
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... infections are common causes ... glomerular #testing #workup ... #diagnosis #glomerulonephritis ... #nephrology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... chest wall, and low ... (to support a diagnosis ... #diagnosis #testing
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... infections are common causes ... glomerular #disease #workup ... #diagnosis #initial ... #testing #nephrology
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