19 results
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin ... of people with low ... many people with low ... the metabolic products ... #Nutrition #Hematology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... serum [K+] to be ... ketone bodies are ... thus, the body produces ... DiabeticKetoacidosis #DKA #pathophysiology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
patients • Avg age ... late adulthood • Diagnosis ... : • Low serum IgG ... 300 mg/dL) • Low ... DDX - Other causes
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
protease activity - A low ... If the value is low ... Fibrin degradation products ... Mild-to-moderate elevation Serum ... #Workup #Hematology
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
Plasma D-dimer is a product ... , which can cause ... specificity is 0-18% How ... Ddimer #dimer #pathophysiology ... #diagnosis #age
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... factor level • Low ... classification #rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusions #diagnosis ... #management #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... stimulates our body to produce ... levels: realllly low ... - Some tumors produce ... about secondary causes
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
endogenous ACTH • Serum ... in cases in which ... autoantibody tests - Serum ... , the CRH will produce ... Evaluation #laboratory #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis