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Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... #Syndrome #Comparison ... #Algorithm #Nephrology ... #Diagnosis
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Diseases Nephrotic ... other elements Nephritic ... differential #spectrum #diagnosis ... #nephrology #nephritic ... #nephrotic #comparison
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Differentiation Between Nephrotic ... Syndrome and Nephritic ... Syndrome == Nephrotic ... #Comparison #Table ... #Nephrology #Diagnosis
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
Diagnosis of ascites ... according to the serum ... Biliary leak, Nephrotic ... #gradient #hepatology ... #differential #diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... - Nephritic and ... Nephrotic Syndromes ... #Proteinuria #Nephrology ... #Diagnosis
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG)

SAAG ≥ 1.1:
 • Cirrhosis
 • Portal
Diagnosis Table ... - Serum Ascites ... < 1.1: • Nephrotic ... #Table #Serum # ... #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... hypertension (SAAG ... 1.1 g/dL) - Nephrotic ... #Causes #diagnosis ... #differential #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... Gradient (SAAG) ... without cirrhosis - Nephrotic ... #Serum #Ascites ... #hepatology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... #diseases #nephrology ... #pathology #comparison ... #table #diagnosis
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... - Differential Diagnosis ... Protein-poor: • Nephrotic ... #Algorithm #Hepatology ... #causes