12 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Diagnosis Framework ... sensitivity of serum ... #AIDS #opportunistic ... InfectiousDiseases #Neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
membrane into the CNS ... collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of serum ... Hyophosphatasia #hepatology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
• Risk: Can produce ... (It's usually low ... Lymphadenopathy, CNS ... Constitutional symptoms ... #AIDS #pulmonary
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Milk • Food products ... fortuitum can produce ... mucogenicum • HIV ... Hematologic malignancy ... • Clinical (Symptoms
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Related Acute Lung ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung ... RBCs binds to serum ... Hypothermia: Due to low ... Extremely rare - HIV ... #Transfusion #diagnosis
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Specificity: - Serum ... infection (IFI) in hematologic ... or other blood products ... Specificity - Serum ... Galactomannan #diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
dissemination occurs and produces ... yeast • At risk: AIDS ... protein level • A low ... prep CSF and serum ... Aspergillosis Pathophysiology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... Differential Diagnosis ... , and elevated serum ... , lymphopenia, low ... Induced Lupus: • Symptoms