7 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... renal tubular acidosis ... #Nephrology #Diagnosis ... #Differential #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... 4) Serum Uric Acid ... salt wasting By Rachel ... #nephrology #sodium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) ... ratio 0.5%) Differential ... Renal tubular acidosis ... #Syndrome #diagnosis ... #nephrology #management
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Bartter syndrome, Gitelman ... the excretion of sodium ... urine #Algorithm #nephrology ... #differential # ... diagnosis
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
Ascites - Diagnosis ... : cell count + differential ... protein, culture • Serum-ascites-albumin-gradient ... (SAAG): > 1.1 g ... cardiac ascites 1) Sodium
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Diagnosis ECF ... chronic respiratory acidosis ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman ... #nephrology
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
dysfunction - K+ deficits ... diabetes insipidus Differential ... Diagnosis: Diabetes ... Sodium, Urine Sodium ... #management #nephrology