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SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... • Pustular skin ... dermatoses • Skin ... Rule out other causes ... osteoarticular and skin
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture ... antibiotics as a cause ... Toxoplasmosis, Entamoeba Skin ... Auto-Inflammatory: PAPA, SAPHO ... Auto-Inflammatory: SAPHO
Drugs Causing Acute Pancreatitis Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
ID Ddx: Diarrhea in a transplant recipient - Bacterial: C.diff, Campy, Salmonella, Aeromonas, E.coli - Viral: CMV, noro,
Viral: CMV, noro, sapo ... Transplant #TxID #SOT #Causes
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Pustular Skin Lesions ... to inflammatory skin ... SAPHO syndrome ( ... osteitis) - Pustular skin ... #Pustular #Skin
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Nodosum #Mnemonic #Causes
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
within GI and URT causes ... Maternal viremia causes ... that persists as skin ... evasion techniques cause ... > Inflammation causes
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Bone/Joint Causes ... thrombophlebitis Skin ... Causes of Leg Pain ... Brittle nails - Skin ... ulcers - Shiny skin
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... Diagnosis #Algorithm #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... • Skin and/or ... diagnosis #algorithm #causes
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