10 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Sarcoidosis • GPA ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... ) VA Joint Chiefs ... #differential # ... diagnosis #comparison ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... surfaces of the joints ... vasculitis #Dermatologic ... #dermatology #rash ... #diagnosis #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential ... Diagnosis Framework ... - GPA Cutaneous ... #dermatology #rheumatology ... diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... vasculitis - GPA ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
interphalangeal joints ... ulcerations • Skin ... 50% of cases • Skin ... #rheumatology # ... dermatology #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
late-onset nemaline myopathy ... Scleromyxedema (CNS+GI+CVS+joints ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Still disease, dermatomyositis ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... #Rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
interphalangeal joints ... : • ILD was diagnosed ... #diagnosis #management ... #rheumatology # ... dermatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... ) • Anti-Mi2 (skin ... Syndrome: Fever, joint ... #rheumatology # ... differential #diagnosis