6 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... myopathy) VA Joint ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
interphalangeal joints ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... exclusion Necrotizing Autoimmune ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... - Differential ... ) • Anti-Mi2 (skin ... Syndrome: Fever, joint ... differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Still disease, dermatomyositis ... Arthritis: • Joint ... #Rheumatology