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antinxp2 antinxp2dm classification dermatologic erythematosus gpa granulomatosis monoclonal myopathies myopathy myositis oncology pain paraproteinemias rash rashes sle systemic vasculitides vasculitis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... reticularis Differential ... #GPA #dermatology ... #rash #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Still disease, dermatomyositis ... Arthritis: • Joint ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Microscopic Polyangiitis ... inflammation Others: • Lupus ... vesicular eruption - Joints ... such as systemic lupus ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
interphalangeal joints ... : • ILD was diagnosed ... #diagnosis #management ... #rheumatology # ... dermatology
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