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management oncology classification clinical erythematosus hematology lupus manifestations monoclonal myelodysplastic pain paraproteinemias polychondritis rashes relapsing signs sjogrens symptoms systemic vasculitides
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... : CTD: SLE, RA related ... : • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Autoimmune manifestations ... dermatomyositis, SLE ... #differential # ... diagnosis #dermatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(25-75%): Inflammatory ... ) • Cutaneous Lesions ... disease) Differential ... Arthritis, AS Treatment ... #Syndrome #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Behçet Syndrome ... : - Ocular inflammatory ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... 3rd Decade Skin ... permanent alopecia Differential ... • Non-autoimmune ... rheumatologic diseases
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... • Behcet syndrome ... #Differential #Diagnosis ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... Scleromyxedema (CNS+GI+CVS+joints ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment ... #Rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... • Inner ear • Skin ... cases such as: • SLE ... Sarcoidosis • Behcet ... affected tissue Treatment
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