6 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
(GPA) Skin involvement ... Rarely dominate the clinical ... • EGPAHenoch-Schönlein ... cryoglobulinemia ... #GPA #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Crohn's disease Palpable ... vasculitis • Henoch ... Schönlein purpura ... Sarcoidosis • GPA ... #rashes #differential
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Henoch Schonlein ... Palpable purpura ... suggestive of Henoch-Schonlein ... #Schonlein #Purpura ... #photo #dermatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... triad of Palpable ... associated vasculitis - GPA ... polyangiitis ... IgA vasculitis (Henoch-Schönlein
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Microscopic Polyangiitis ... often present • Henoch ... Schonlein Purpura ... -> causing palpable ... • ANCA (Dx: GPA
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
MPO > PR3 60/ GPA ... often present) Henoch ... Schonlein Purpura ... ) • Palpable purpura ... / ANCA + MPO) Cryoglobulinemic