11 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Pauci-immune vasculitis ... : Vasculitis: ... • Henoch-Schönlein ... #dermatology #rash
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Schonlein Purpura ... (HSP, IgA Vasculitis ... #Schonlein #HSP ... #IgA #Vasculitis ... #dermatology #skin
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Henoch Schonlein ... Leg Rash - Palpable ... Low Platelets or Vasculitis ... Palpable = vasculitis ... #photo #dermatology
Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
Rash Febrile ... Endocarditis, Henoch-SchönIein ... - Autoimmune Vasculitis ... #Diagnosis #Dermatology ... #Skin
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
OF PALPABLE PURPURA ... : Vasculitis: ... • Ig A vasculitis ... /HSPCryoglobulinemia ... HCV, HBV Not Vasculitis
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vessel: Petechiae, Palpable ... purpura, Hemorrhagic ... : - Ig A (HSP) ... Urticarial/LCV) - Cryoglobulinemic ... #skin #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
vasculitis • ... Henoch Schönlein ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome • Vasculitis ... #differential #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Infection - Vasculitis ... Schonlein Purpura ... Rash: - Purpura ... Vasculitis (lupus ... RA, Sjogren's, GPA
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often present • Henoch ... Schonlein Purpura ... tract, and often causes ... Vasculitis - Skin ... mucositis - Rash
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- GPA, EGPA, microscopic ... • IgA vasculitis ... (Henoch-Schönlein ... small-vessel vasculitis ... • Vasculitis