10 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis ... #algorithm #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... Vasculitis (Henoch-Schönlein ... Elevated serum IgA ... - Dominant IgA ... #Rheumatology #
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Schonlein Purpura ... (HSP, IgA Vasculitis ... #Henoch #Schonlein ... #HSP #IgA #Vasculitis ... #dermatology #skin
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Henoch Schonlein ... suggestive of Henoch-Schonlein ... purpura (IgA), ... #Schonlein #Purpura ... #dermatology #HSP
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Differential Diagnosis ... • Henoch-Schönlein ... #dermatology #rash ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
vasculitis • Henoch ... Schönlein purpura ... Sarcoidosis • GPA ... #differential #diagnosis ... #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... associated vasculitis - GPA ... • IgA vasculitis ... (Henoch-Schönlein ... classification #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... infection - RMSF - Henoch ... Schonlein Purpura ... cryoglobulins • Skin ... #dermatology #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
MPO > PR3 60/ GPA ... Schonlein Purpura ... (IgA Vasculitis ... , IgA (cmpkx deposits ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... often present • Henoch ... Schonlein Purpura ... (IgA vasculitis ... #rheumatology #