12 results
Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
Algorithm for Diagnosis ... Endocarditis, Henoch-SchönIein ... #Purpuric #Petechiae ... #Algorithm #Diagnosis ... #Dermatology #Skin
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #rheumatology
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Palpable Purpura ... Schonlein Purpura ... #Purpura #Henoch ... #clinical #photo ... #dermatology #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
, Palpable purpura ... • Palpable purpura ... • Henoch-Schönlein ... #dermatology #rash ... #diagnosis #rheumatology
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Henoch Schonlein ... Palpable purpura ... suggestive of Henoch-Schonlein ... purpura (IgA), ... #dermatology #HSP
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
infection - RMSF - Henoch ... Schonlein Purpura ... Rash: - Purpura ... cryoglobulins • Skin ... #Causes #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Urticarial/LCV) - Cryoglobulinemic ... - GPA Cutaneous ... #dermatology #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... vasculitis/HSP • Cryoglobulinemia ... Differential #Diagnosis #hematology ... #rheumatology # ... #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
vasculitis • Henoch ... Schönlein purpura ... Sarcoidosis • GPA ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Clinical triad of Palpable ... associated vasculitis - GPA ... • IgA vasculitis ... (Henoch-Schönlein ... classification #rheumatology