9 results
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Schonlein Purpura ... (HSP, IgA Vasculitis ... #Purpura #Henoch ... #IgA #Vasculitis ... #dermatology #skin
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #Vasculitis #differential ... #rheumatology
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Henoch Schonlein ... Palpable purpura ... Palpable = vasculitis ... suggestive of Henoch-Schonlein ... purpura (IgA),
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... reticularis Differential ... • Henoch-Schönlein ... pneumonia with glomerulonephritis ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Crohn's disease Palpable ... Henoch Schönlein ... Sarcoidosis • GPA ... #joint #pain #skin ... #rashes #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often present • Henoch ... Schonlein Purpura ... (IgA vasculitis ... vesicular eruption - Joints ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
infection - RMSF - Henoch ... Schonlein Purpura ... cryoglobulins • Skin ... #Causes #dermatology ... #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Schonlein Purpura ... (IgA Vasculitis ... skin) • Palpable ... purpura, joint
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Glomerulonephritis ... Clinical triad of Palpable ... - GPA, EGPA, microscopic ... • IgA vasculitis ... (Henoch-Schönlein