6 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #Vasculitis #differential ... #rheumatology
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Henoch Schonlein ... Tip: To differentiate ... suggestive of Henoch-Schonlein ... purpura (IgA), ... #Schonlein #Purpura
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Petechiae, Palpable purpura ... Petechiae • Palpable purpura ... Vesicles overlying purpuric ... • Henoch-Schönlein ... purpura • Mixed
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Schonlein Purpura ... (IgA vasculitis ... erythematous nodules, purpura ... causing palpable purpura
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... triad of Palpable purpura ... • IgA vasculitis ... (Henoch-Schönlein ... purpura) • Cutaneous
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... : • Purpura, ischemic ... Schonlein Purpura ... (IgA Vasculitis ... , IgA (cmpkx deposits