11 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... syndrome • Giant cell ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology ... #rheumatology
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Diagnosis? ... differential: basal cell ... ca, squamous cell ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... microglobulin Treatment ... #workup #oncology ... #hematology
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Raised off of the skin ... scarring Benign T-cell-mediated ... weeks Severe T-cell-mediated ... Drug #Reactions #dermatology ... #clinical #comparison
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
the mainstay of treatment ... lesions, or localized ... hematopoietic stem cell ... #comparison #table ... #dermatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... heaped, wart-like lesions—Condyloma ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
lesions: antihelix ... auricular papules Clinical ... CD4+ and CD8+ T cell ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
lesion which may ... CLM most commonly ... No treatment is ... migrans #skinRash #dermatology ... #clinical #photo
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... MM, the plasma cell ... #Solitary #Cell ... #Workup #Hematology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
lesions: antihelix ... carcinoma • Clear cell ... adenocarcinoma • Non-small-cell ... #management #rheumatology ... #dermatology