4 results
Acanthosis Nigricans: Velvety appearing, hyperpigmented skin. Associated with diabetes and a 
number of other disorders. Multiple
Acanthosis Nigricans ... hyperpigmented skin ... Multiple skin tags ... Goldberg, M.D. - UCSD ... Images #Clinical #Dermatology
Cutis Verticis Gyrata: Idiopathic development of excess folds and furrows within the skin of the head.
Associated
furrows within the skin ... mental retardation, acromegaly ... Goldberg, M.D. - UCSD ... Images #Clinical #Dermatology ... Gyrata #Photo #UCSDH
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
facial features, soft ... , hair growth, skin ... tags, skin thickening ... , acanthosis nigricans ... Diagnosis #Management #Endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... hands/feet - Soft ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology