69 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... #LiverInjury #Hepatology ... #Pharmacology # ... Causes #DILI
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
practices that could cause ... , Quantitative IgA ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology
Septic Arthritis: Pathogenesis and clinical findings
Notes:
- Septic Arthritis is typically monoarticular & the knee is involved
involved in >50% of cases ... formation - Typical S.A ... most common, but S.A ... . can also be caused ... SepticArthritis #pathophysiology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
#Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
gout #uricacid #pathophysiology ... #pharmacology # ... rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Normal Complement: IgA ... diagnosis #algorithm #rheumatology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... number of pain crises ... Benefits #SickleCell #pathophysiology ... #pharmacology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
cause quadriplegia ... invade URT & via hematologic ... within GI and URT causes ... CNS and hematologic ... peds #pediatrics #pathophysiology