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rheumatology classification antiarrhythmics diagnosis differential hydroxychloroquine vasculitis adverseeffects algorithm benefits glomerulonephritis levels management measurement phases progressive rapidly risks rpgn serum
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... Normal Complement: IgA ... diagnosis #algorithm #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... rare with ~100 cases ... Hydroxychloroquine #hcq ... Risks #Benefits #Lupus ... #pharmacology #
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
current) causing ↓SA ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology ... #cardiology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... current) causing ↓SA ... Classification #Classes ... #pathophysiology ... #phases #cardiology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Schonlein Purpura (IgA ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... • HIV • HBV HCV
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