10 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... Hyperlipidemia, ↓ SSA-associated ... rare with ~100 cases ... Hydroxychloroquine #hcq ... #Lupus #pharmacology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... l MD SOAP) - Risks ... PLT in selected cases ... , Quantitative IgA ... Differential #Diagnosis #Causes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... Normal Complement: IgA ... diagnosis #algorithm #rheumatology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Physiologic Causes ... Pathologic Causes ... - Obesity - Cirrhosis ... #causes #cardiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
current) causing ↓SA ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology ... #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... current) causing ↓SA ... Classification #Classes ... #pathophysiology ... #phases #cardiology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Infectious: HAV, HBV, HCV ... Due to synthesis rises ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
effusion, INC risk ... primary biliary cirrhosis ... Nephrogenic DI Hematologic ... Malignancy Risk ... lubricants • Pharmacologic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Schonlein Purpura (IgA ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... • HIV • HBV HCV