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Pathophysiology Euglycemic DKA - Mechanism of SGLT-2 Inhibitors #Pathophys #Endocrine #Euglycemic #DKA #SGLT2 #Mechanism
Pathophysiology Euglycemic ... - Mechanism of SGLT ... Pathophys #Endocrine #Euglycemic ... #DKA #SGLT2 #Mechanism
Pathophysiology of Euglycemic DKA in SGLT2 Inhibitors
 • Kidney: Glycosuria, Natriuresis, ↑ Ketone bodies reabsorption
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Pathophysiology of Euglycemic ... DKA in SGLT2 Inhibitors ... Ketogenesis → Euglycemic ... @priti899 #Euglycemic ... #DKA #SGLT2i #Inhibitors
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... and Euglycemic ... Risk factors for euglycemic ... in those on an SGLT2i ... #Euglycemic #DKA
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Ketoacidosis (EuDKA) SGLT2 ... @accpcardprn #Euglycemic
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
glucose, ask if on SGLT2 ... - Eugylcyemic ... ketoacidosis in SGLT2 ... inhibitors and SGLT2
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... Action: Inhibits SGLT2 ... candidiasis) • Euglycemic ... EricsMedicalLectures/featured #SGLT2
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Euglycemic ... variant seen with SGLT
SGLT2 Inhibitors and Cardiovascular Pathophysiology

#SGLT2i #Inhibitors #Cardiovascular #Pathophysiology
SGLT2 Inhibitors ... Pathophysiology #SGLT2i
Perioperative Medications - Which Medications to Hold or Continue?
Aspirin - Continue
 • Aspirin should be continued
Empagliflozin (SGLT2 ... reports of AKI and euglycemic
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
Clinical Trials of SGLT2 ... ASCVD; signal for SGLT2i ... risk; signal for SGLT2i ... outcomes trial in SGLT2i ... mcclaffertyMD #SGLT2