71 results
SGLT2 Inhibitors and Cardiovascular Pathophysiology

#SGLT2i #Inhibitors #Cardiovascular #Pathophysiology
SGLT2 Inhibitors ... Pathophysiology #SGLT2i ... #Inhibitors #Cardiovascular
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
comparison between SGLT ... -2 inhibitors - ... (Steglatro) #diabetes ... cardiovascular #renal #SGLT2i ... #Inhibitors #pharmacology
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
Clinical Trials of SGLT2 ... inhibitors in CVD ... HF outcomes in HFrEF ... HF outcomes in HFrEF ... #inhibitors #EBM
#diabetes #T2DM #antidiabeticagents #oraldiabeticagents

FIGURE 9.1 Glucose-lowering medication in type 2 diabetes: overall approach. For appropriate context,
#diabetes #T2DM ... dipeptidyl peptidase 4 inhibitor ... receptor agonist; SGLT2i ... , SGLT2 inhibitor ... Diabetes Care 19
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
drugs Other than SGLT2i ... alpha-glucosidase inhibitor ... receptor agonist SGLT2i ... cotransporter-2 inhibitor ... type 2 diabetes;
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
@DharSaty #HFrEF ... sodium-glucosecotransporter-2inhibitors ... #SGLT2i #reninangiotensinaldosteronesysteminhibitors
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

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Ejection Fraction (HFrEF ... -2 Inhibitor • ... Beta-Blocker + SGLT ... -2 Inhibitor → ARNI ... #Failure #CHF #HFrEF
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Mechanism #Nephrology #SLGT2 ... #Inhibitors #Reabsorption
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... in those on an SGLT2i ... is closed • SGLT2 ... inhibitor should ... Kat_Watson #SGLT2
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... Mechanisms of Action: Inhibits ... SGLT2 (sodium/glucose ... • Euglycemic diabetic ... #Summary #DM2 #diabetes