36 results
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Pathophysiology #Mechanism #Nephrology ... #SLGT2 #Inhibitors
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Acetazolamide, others SGLT2 ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... summary #table #nephrology
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
Clinical Trials of SGLT2 ... ASCVD; signal for SGLT2i ... risk; signal for SGLT2i ... outcomes trial in SGLT2i ... mcclaffertyMD #SGLT2
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
comparison between SGLT ... cardiovascular #renal #SGLT2i ... #Inhibitors #pharmacology
Indications for and pharmacological properties of approved SGLT2 inhibitors

Canagliflozin - Dapagliflozin - Empagliflozin - Ertugliflozin

#SGLT2 #Inhibitors
properties of approved SGLT2 ... Ertugliflozin #SGLT2 ... #Inhibitors #pharmacology
#SGLT2i #patientinfo #nephrology
#SGLT2i #patientinfo ... #nephrology
Pathophysiology of Euglycemic DKA in SGLT2 Inhibitors
 • Kidney: Glycosuria, Natriuresis, ↑ Ketone bodies reabsorption
 •
Euglycemic DKA in SGLT2 ... Euglycemic #DKA #SGLT2i ... pathophysiology #nephrology
#visualabstract #sglt2i #nephrology
#visualabstract ... #sglt2i #nephrology
Stepwise Approach to Prescription of SGLT2 inhibitors 

Anticipatory Guidance 
• Consider diuretic dose reduction 
Patient Counseling
Prescription of SGLT2 ... Guidance • Consider diuretic ... endocrinologists #SGLT2
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
Flowchart to diuretic ... Total loop diuretic ... , intravenous; SGLT2 ... a single loop diuretic ... #Diuretic #Diuresis