20 results
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
comparison between SGLT ... -2 inhibitors - ... cardiovascular #renal #SGLT2i ... #Inhibitors #pharmacology
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Pathophysiology #Mechanism #Nephrology ... #SLGT2 #Inhibitors
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
CARBONIC ANHYDRASE INHIBITORS ... Acetazolamide, others SGLT2 ... INHIBITORS • ... #Medications #Pharmacology ... summary #table #nephrology
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
Clinical Trials of SGLT2 ... ASCVD; signal for SGLT2i ... risk; signal for SGLT2i ... outcomes trial in SGLT2i ... mcclaffertyMD #SGLT2
Indications for and pharmacological properties of approved SGLT2 inhibitors

Canagliflozin - Dapagliflozin - Empagliflozin - Ertugliflozin

#SGLT2 #Inhibitors
properties of approved SGLT2 ... inhibitors Canagliflozin ... Ertugliflozin #SGLT2 ... #Inhibitors #pharmacology
Pathophysiology of Euglycemic DKA in SGLT2 Inhibitors
 • Kidney: Glycosuria, Natriuresis, ↑ Ketone bodies reabsorption
 •
Euglycemic DKA in SGLT2 ... Inhibitors • ... Euglycemic #DKA #SGLT2i ... #Inhibitors #pathophysiology ... #nephrology
Stepwise Approach to Prescription of SGLT2 inhibitors 

Anticipatory Guidance 
• Consider diuretic dose reduction 
Patient Counseling
Prescription of SGLT2 ... inhibitors ... Guidance • Consider diuretic ... endocrinologists #SGLT2 ... #Inhibitors #Prescription
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... SGLT2 (sodium/glucose ... leading to osmotic diuresis ... EricsMedicalLectures/featured #SGLT2 ... #Inhibitors #Pharmacology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... are similar to diuretics ... /ambcarerx #SGLT2 ... #Inhibitors #Pharmacology
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
Flowchart to diuretic ... Total loop diuretic ... , intravenous; SGLT2 ... transporter 2 inhibitor ... #Diuretic #Diuresis