13 results
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia

- BWH Medicine Chiefs @BrighamChiefs

#Serotonin #Syndrome #Neuroleptic
Comparison - Serotonin Syndrome ... #Serotonin #Syndrome ... Malignant #Catatonia #NMS ... #SS #comparison ... diagnosis #management #treatment
Treatment of NMS
 Dopamine antagonists should be discontinued immediately in patients suspected of NMS. Like SS,
Treatment of NMS ... Like SS, the mainstay ... treatment of NMS ... NeurolepticMalignant #Syndrome ... #NMS #Treatment
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Drug-related (NMS ... , serotonin syndrome ... Immunocompromise Treatment ... • Secondary to Treatment ... effect/reaction (ie SJS
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... (SS), Polymyositis ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... (SS), Polymyositis ... Arthritis, Sjögren Syndrome ... Kumfer @AnnKumfer #Antinuclear
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... 30-40% Target: SS-A ... SLE-SSc-AlM overlap syndromes ... Lupusreference #Antinuclear
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... Walid Malki, MD, MS ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... - β-lactam antibiotics ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... hypofunction • Antibodies ... ab • RF • Antinuclear ... antibodies ≥ 1: ... Adenocarcinoma Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
isoniazid) • Antibiotics ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... diagnosis #hematology #oncology