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How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis: https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext #Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Pathophysiology #Mechanism #Nephrology ... #SLGT2 #Inhibitors
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
SGLT2 Inhibitors ... and Euglycemic DKA ... for euglycemic DKA ... alcohol consumption Diagnostic ... #Euglycemic #DKA
Pathophysiology Euglycemic DKA - Mechanism of SGLT-2 Inhibitors #Pathophys #Endocrine #Euglycemic #DKA #SGLT2 #Mechanism
Pathophysiology Euglycemic DKA ... Endocrine #Euglycemic #DKA ... #SGLT2 #Mechanism
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
Ketoacidosis (AKA ... Ketoacidosis (DKA ... • Euglycemic DKA ... State (HHS) • DKA ... #differential #diagnosis
Stepwise Approach to Prescription of SGLT2 inhibitors Anticipatory Guidance • Consider diuretic dose reduction Patient Counseling
Prescription of SGLT2 ... • Symptoms Of DKA ... endocrinologists #SGLT2
Metabolic Acidosis with Anion Gap - KILU Mnemonic K - Ketoacidosis • DKA - With normal glucose, ask if
Ketoacidosis • DKA ... glucose, ask if on SGLT2 ... ketoacidosis in SGLT2 ... inhibitors and SGLT2 ... Metabolic #Acidosis #diagnosis
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
DKA DIAGNOSTIC CRITERIA ... 10% to 30% of DKA ... common trigger for DKA ... 2.6% to 3.2% of DKA ... #DKA #EDKA #Insulin
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... Action: Inhibits SGLT2 ... ketoacidosis (DKA ... EricsMedicalLectures/featured #SGLT2
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Ketoacidosis (DKA ... ) - Diagnosis and ... , and death DKA ... 200 mg/dL #DKA ... #Ketoacidosis #Diagnosis
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
DKA vs HHS - Think ... of DKA and HHS ... look like overlap DKA ... BrighamChiefs #DKA ... comparison #laboratory #diagnosis
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